Endocrine Abstracts

Introduction: Denosumab is a monoclonal antibody indicated in the treatment of postmenopausal osteoporosis. Hypocalcemia is a rare adverse effect.Case report: We present the case of a 58-year-old woman with a clinical history of bariatric surgery in 2001 and osteoporosis with multiple vertebral and hip fractures. Under treatment with Zinc sulphate, Vitamin A, 25-OH-vitamin D, calcium and iron. She came to the A&E for general malaise, generalized weak...

Introduction: 46,XX testicular disorder of sex development (DSD) is a rare syndrome, which is characterized by a female karyotype in discordance with a male phenotype. It is presented with primary hypogonadism, gynecomastia and infertility. About 80–90% of 46,XX testicular DSD cases are positive for SRY gene. Appearance of external genitalia and masculinization are usually normal in 46,XX SRY-positive casesClinical case: A 41-year-old male came with...

Background and Objective: Semaglutide, a glucagon-like peptide 1 (GLP1a) receptor agonist, reduces the risk of major adverse cardiovascular events in patients with type 2 diabetes mellitus (DM2). An oral version of semaglutide is now available, and patients may prefer it to the subcutaneous form. Our objective was to compare the effectiveness and safety of both formulations in real life.Methods: Retrospective real-world efficacy analysis including aGLP1-...

Introduction: Primary aldosteronism (PA) is the most common cause of secondary hypertension (5–10%) and it is underdiagnosed. Less than 50% of patients with PA have hypokalemia. The tests for determinate subtype of PA are cross-sectional imaging (adrenal CT or MRI) and adrenal vein sampling (AVS). The AVS seems to be important to direct appropriate therapy and surgery is the preferred treatment for patients with unilateral disease.Material and metho...